Page 67 - Canine-Diseases
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disease characterized by the presence of antibodies to nucleic acid  inactivity of the hair follicle. On epilation, the root or bulb of the
        and/or antibodies to red blood cells, platelets, lymphocytes, clotting  hair appears rough, non-pigmented, with a club or spear-shaped
        factors, and thyroglobulin. The disease can result in deposition of  appearance. The normal hair coat generally consists of hairs in
        immune  complexes  or  autoimmune  disease.  Immune  complex  either  anagen  (active  growth) or telogen  phase.  Intermediate
        deposition can cause vasculitis,  meningitis,  neuritis, and joint  catagen hairs are less commonly found. The hairs in telogen are
        and skin disease. Autoimmune  disease may result in hemolytic  more easily shed than those in anagen.
        anemia, thrombocytopenic purpura, proteinuria, dermatitis
        and symmetrical polyarthritis,  which are the most common  Telogen effluvium: Is when some stress causes hair roots to be
        manifestations of SLE in dogs. The definitive causes for SLE are  pushed prematurely into the resting state. Many female dogs who
        unidentified, but exposure to ultraviolet light may exacerbate the  are nursing puppies will lose a large amount of hair. Such a dog is
        disease.  Specific  signs  of  SLE  may  include  lethargy,  anorexia,  often said to be ‘blowing her coat’ or ‘telogen effluvium’. During
        lameness that appear to move from limb to limb, fever, ulcers  pregnancy and other stresses including  infections,  hairs may
        at mucocutaneous junctions like lips, enlarged lymph nodes,  enter telogen prematurely, and do so in large numbers. Hormone
        enlarged spleen, enlarged liver, muscle atrophy (wasting), and skin  changes in female dogs may also play a role in this change.
        signs may include redness, thinning, localized ulceration, loss of
        pigment, and thinning or loss of hair. Some breeds are predisposed   Testicular torsion: Also known as torsion of the spermatic cord,
        to developing SLE. They tend to be medium to large dogs. These   causes rotation of the testicle, ultimately causing obstruction to
        include  German Shepherds, Old  English  Sheepdogs,  Afghan   venous drainage. It is uncommon in dogs and usually a sequel
        Hounds, Irish Setters, Shetland Sheepdogs, Collies, Beagles, and   to  neoplastic  transformation  of a  retained  testicle  because  the
        Poodles.                                               increased mass and greater mobility predisposes to rotation along
                                                               the pedicle. Descended testicles that undergo torsion are usually
                                 T                             non-neoplastic. The affected testicle is larger than the contralateral
                                                               testicle  with  a  diffusely  hypoechoic  parenchyma.  The  scrotum,
                                                               epididymis, and spermatic  cord are thickened.  With chronic
                                                               testicular torsion, the testicle will become smaller and may become
                                                               more heterogenous. The predominant clinical signs are pain, stiff
        Tail gland hyperplasia (Supracaudal gland hyperplasia):  stilted gait, and the presence of an abnormally swollen testicle (if
        Also known as stud tail, is the inflammation or infection of the  located within the scrotum). If an intraabdominal testicular torsion
        supracaudal gland (aka tail gland, violet gland), which is modified  is  present,  pain, lethargy, anorexia,  and  vomiting  can  occur.
        sebaceous gland that secretes sebum. Cell hyperplasia may occur  Testicular torsion is also referred to as orchitis and epididymitis as
        with primary or secondary seborrhoea, or as a result of elevated  these terms refer to symptoms of inflammation that are caused by
        blood androgen levels.  Tail  hair may  initially  mask the  early  infection, trauma or metastasis.
        signs of hyperplasia, but friction over the area or pressure from
        hyperplastic cells on the hair follicles  may result in hair loss.  Testicular tumors:  Are considered  one  of the  most common
        Underlying skin may show any / all of scale, greasiness and  tumors of the  male  reproductive tract  (90%), most commonly
        hyperpigmentation.  Secondary  infection  is rare,  appearing  as  in older intact dogs. The three most common types of testicular
        acne-like  gland  infection. Advanced  cases  may  appear  nodular  tumors are Sertoli cell  tumors, interstitial  (Leydig)  cell  tumors
        either due to uneven hyperplasia, cyst formation or infection.   and seminomas. About one third of dogs that develop a tumor
                                                               will have more than one of these types of tumors present. Other
        Tapeworms (Cestodiasis): The most common tapeworm of dogs  types  of  testicular  tumors  (i.e.  embryonal  carcinoma,  lipoma,
        is Dipylidium caninum, which is spread by ingesting fleas and lice.  fibroma,  hemangioma,  chondroma,  teratoma)  can  occur  but  are
        Also common is  Taenia pisiformis, spread by ingesting  rabbits  rare.  These  tumors are  slow to metastasize  but may  spread to
        and rodents. Rare tapeworm infections are caused by species of  lymph nodes. Testicular tumors produce excessive hormones such
        the genera Echinococcus, Mesocestoides, Diphyllobothrium, and  as estrogen or testosterone. Sertoli cell tumors have a higher rate
        Spirometra.  Adult tapeworms reside in the small  intestines  of  of spread than other testicular tumors. Studies have indicated that
        dogs. Motile proglottids (dried, white to cream colored segments,  cryptorchidism (absence of one or both testes from the scrotum)
        or pieces,  of tapeworm)  may  be seen in  the  perianal  region  as  is  one  of  the  most  important  contributing  factors  to  testicular
        they exit the animal, in the pet’s environment (e.g. on bedding),  cancer. Exposure to environmental carcinogens are other factors
        or in the fecal material itself. Dogs may bite or lick the anus, or  that attribute to tumorogenesis. Clinical signs of testicular tumors
        drag their hind quarters across the floor in response to the itching.  include soft swellings in one or both testicles, a single enlarged
        Cestodiasis poses a zoonotic health risk.  Treatment  to destroy  testicle or asymmetric testicles, generalized scrotal enlargement,
        tapeworms is critical to avoid transmission to humans (typically  and infertility. Hair and skin changes may include symmetrical
        children).                                             hair loss, brittle hair, poor hair regrowth after shaving the coat,
                                                               thin skin, hyperpigmentation (darkening of the skin) and a stripe
        Telogen  defluxion:  In dogs it  is a  form  of alopecia.  Telogen   of red inflammation along the midline of the prepuce. Other signs
        defluxion is a disorder which causes excessive hair shedding in   include nipple elongation, mammary enlargement, penile atrophy,
        dogs. It is caused by extreme stress on the body which has occurred   preputial swelling and sagging, testicular atrophy of the unaffected
        in the last 1 to 3 months. Telogen describes the period of rest or   (noncancerous testicle),  prostatic atrophy or enlargement,  and



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