Page 21 - Canine-Diseases
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disease include  ataxia  (loss of coordination),  wobbling when  Huskies, Labradors and Golden Retrievers can have darker noses
        walking, and mild hind leg weakness. In the intermediate stage,  in the summer months and lighter noses in the winter. These same
        the limbs become weak where the dog begins to buckle and the  breeds plus German Shepherds, Samoyeds, Afghan Hounds and
        weakness progresses until the dog is unable to walk in the hind  Dobermans (among others) can also experience  a gradual or
        limbs. Loss of urinary and fecal continence  and weakness in  waxing and lightening or fading of their nose color over time. This
        front limbs  are  observed in the  advanced  stage.  Although  the  condition is known as “Dudley Nose”. Contact dermatitis/irritation
        disease is common in several breeds, including German Shepherd  can cause depigmentation as can certain chemicals in rubber that
        Dogs, Corgis, Boxers, Chesapeake  Bay Retrievers,  Rhodesian  can affect the production of melanin pigment where the rubber
        Ridgebacks, and Standard Poodles, it can occur in other breeds  touches the skin. In addition, immune-mediated diseases (discoid
        and mixed-breed dogs as well. The typical age of onset is between  lupus erythematosus), hormonal disorders (imbalances of thyroid,
        8-14 years of age, and both sexes are equally affected.  adrenal or sex hormones) can alter pigmentation as can bacterial
                                                               and fungal infections and even cancers (neoplasias).
        Dementia: Dog dementia or canine cognitive dysfunction (CCD),
        is an umbrella term for four separate cognitive forms, is an age-  Dermal  fragility  syndrome  (Ehlers-Danlos-like  syndrome):
        related neurobehavioral syndrome leading to a decline in cognitive  Related  terms include  primary connective  tissue disease,
        function.  The 4 forms are involutive  depression (depression  cutaneous asthenia, dermatosparaxis,  collagen  dysplasia, fragile
        occurring  in the dog’s later  years), dysthymia  (persistent  mild  skin syndrome,  is a group of connective  tissue disorders that
        depression), hyper-aggression, and confusional syndrome  are characterised by fragile, stretchy and loose skin, caused by a
        (profound decline in cognitive ability). Symptoms include walking  genetic defect in the production of collagen. The clinical signs of
        into corners or other tight spaces and staying there (getting “lost”),  Ehlers-danlos syndrome are fragile skin and laxity in the joints,
        confusion, sleep-wake cycle disturbances, anxiety, low levels of  due to the alterations to collagen structure and density. Even the
        activity, does not greets family members upon arrival, howling,  slightest scratch can damage and tear the skin of affected animals,
        barking  or whining,  pacing,  elimination  disorders,  staring  into  leading to scarring and subcutaneous hematomas, which are hard
        space or walls, and disorientation.                    masses of blood under the skin surface. The deficiency in collagen
                                                               can also affect other tissues of the body, such as the eyes, heart and
        Demodex: Demodectic mange, sometimes just called “demodex”   blood vessels. The condition affects English Springer Spaniels, but
        or “red  mange”, is a common  skin disease  of dogs caused  by   have also been seen in other breeds, which include Dachshunds,
        microscopic mite called Demodex canis which lives in the hair   Beagles, Saint Bernard, German Shepherds, Boxers, Welsh Corgis,
        follicle and sebaceous glands of the host. Under the microscope,   and Manchester Terriers.
        this mite is shaped like a cigar with eight legs and the entire life
        cycle is spent on the host. Two other Demodex species, a short  Dermatophytosis: Is an infection  of keratinized  tissue (skin,
        and long tailed species, rarely cause disease. Demodectic mange  hair, and claws) by one of the three genera of fungi collectively
        most often occurs when a dog has an immature immune system,  called  dermatophytes  -  Epidermophyton,  Microsporum, and
        allowing the number of skin mites to increase rapidly. If localized,  Trichophyton. In dogs it is mainly caused by Microsporum canis
        symptoms are usually mild, with lesions occurring in patches,  (70% of cases), but also by  Microsporum  gypseum (20%) and
        especially  on  the  face,  torso  or legs.  If generalized,  symptoms  Trichophyton mentagrophytes (10%). Under most circumstances,
        will  be  more  widespread  and  appear  across the  body.  These  dermatophytes  grow only in keratinized  tissue, and advancing
        symptoms include alopecia, a redness of the skin (erythema) and  infection  stops  when  reaching  living  cells  or  inflamed  tissue.
        the appearance of scales and lesions. Demodectic mange is not  Lesions in dogs are classically alopecic,  scaly patches  with
        contagious and human demodex cases are rather rare but do occur.  broken  hairs. Dogs may  also  develop  regional  or generalized
                                                               folliculitis  and furunculosis with papules and pustules.
        Dental disease: Canine periodontitis is a bacterial infection of the   Concurrent  overgrowth of  Staphylococcus species is common.
        mouth, is common in dogs. There are four stages of periodontal   Dermatophytosis is commonly called ringworm but there are no
        disease,  progressing  from  plaque  and  mildly  inflamed  gums  to   parasitic worms involved. It is obtained via contact with infected
        established gingivitis (gum disease), and then on to mild and   hair or scale from infected/carrier animals, fomites, or spores in
        ultimately severe periodontitis, which may involve bone and/or   contaminated  soils or indoor environments.  The fungal spores
        tooth loss. Symptoms include halitosis, swollen gums, yellow or   shed from an infected animal can live in the environment for over
        brown teeth, loose or missing teeth, trouble chewing bones, loss of   18 months. Dermatophytosis fungus is more common in hot and
        appetite, and weight loss.                             humid climates. It is contagious, infectious, and can be transmitted
                                                               to people. Zoonosis is possible with all three species, but most
        Depigmentation: A loss of colouration (i.e. melanin) within the   often with M. canis.
        skin due to toxic or inflammatory damage to pigment creating cells
        (melanocytes). Age-associated  graying  is a result  of decreasing   Dermoid sinus: Also known as a pilonidal  sinus, is a tubular
        numbers of melanocytes and occurs most frequently in German   skin defect caused by incomplete separation of the skin and the
        Shepherds, Labradors, Golden Retrievers, and Irish Setters. There   nervous system during embryonic development. The sinus can be
        are other breeds of dogs that are prone to a seasonal lightening   found at any point along the back or neck, but most commonly
        of the nasal planum (the hard, tough, hairless end of their nose).   affects  the  neck  or  upper  spine.  Breeds  known  to  be  affected
        Sometimes referred to as “Snow Nose” these dogs such as Siberian   include Rhodesian Ridgebacks, Phu Quoc Ridgebacks, and Thai


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