Page 45 - Canine-Diseases
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that  are  predisposed  to  MCT  include  Boston  Terriers,  Boxers,  or ulceration  from neoplasia or foreign object), and chronic or
        Pugs,  English  Bulldogs,  Beagles,  Bull  Terriers,  Bullmastiffs,  recurrent gastric dilatation  with or without volvulus were also
        Dachshunds,  Australian  Cattle  Dogs, Cocker  Spaniels,  Fox  associated  with increased  risk of developing  megaesophagus.
        Terriers, Golden Retrievers,  Labrador  Retrievers,  Rhodesian  Symptoms of megaesophagus include  halitosis, fever, rapid
        Ridgebacks,  Schnauzers,  Staffordshire  Terriers,  Shar-Peis,  and  breathing, abnormal lung sounds, muscle weakness, and muscle
        Weimaraners.                                           wasting.  Breeds with  increased prevalence  of  megaesophagus
                                                               include  Wire-haired  Fox  Terriers, Miniature  Schnauzers, Great
        Masticatory muscle myositis (MMM):  Is  an  inflammatory   Danes, German Shepherds, Labrador Retrievers, Newfoundlands,
        disease in dogs affecting the muscles of the jaw. Signs include   Greyhounds, Shar-Peis, and Irish Setters.
        swelling of the jaw muscles and pain on opening the mouth. This
        disease is an autoimmune process in which circulating antibodies  Melanoma:  A malignant  tumor of melanocytes  (melanocytic
        specifically target the masticatory muscles. In chronic MMM there  tumor), the cells responsible for pigment production. They account
        is atrophy of the  jaw  muscles, and  scarring  of the  masticatory  for 5-7% of all canine skin tumors. There are different types of
        muscles due to fibrosis may result in inability to open the mouth  melanocytic tumors like melanocytic nevus, melanocytoma, and
        (trismus). MMM occurs in all  breeds, but appears to be more  malignant  melanoma  which can further divided into cutaneous
        common  in  German  Shepherds, Doberman  Pinschers,  Golden  melanoma,  oral melanoma,  uveal or intra-ocular  melanoma,
        Retrievers, and Labrador Retrievers.                   and limbal (epibulbar) melanoma. Lesions are usually solitary
                                                               and tend to occur on the head, lips, limbs, digits, scrotum, and
        Mastitis: Is a bacterial infection of the mammary glands, mostly   trunk in dogs. About 50% of the melanomas are of the nail beds
        seen in females, usually lactating females. However, male dogs   and foot pads which spread to other sites of the body. Lesions
        can also develop mastitis.  Escherichia coli,  Staphylococci, and   are often ulcerated but otherwise vary in size, shape and colour
        β-hemolytic Streptococci are some of the main bacteria that are   (grey, brown, or black). Tumour may grow up to 10cm diameter
        found to be most commonly involved. Mastitis can quickly change   in dogs. On palpation lesion may be poorly or well circumscribed.
        from a mild, localized infection to an abscess in the mammary   Dog breeds that are  predisposed to  melanoma  include  Scottish
        gland or a potentially deadly systemic illness. Dogs that have had   Terriers, Cocker Spaniels, Gordon Setters, Chow Chows, Vizslas,
        mastitis are more prone to developing it again. Mastitis in dogs is   Miniature  Schnauzers,  Doberman  Pinschers,  Airedale  Terriers,
        categorized into two different types. 1. Acute Septic Mastitis: the   Boston Terriers, Springer Spaniels, Bay Retrievers, and Golden
        female has developed an infection or abscess within a mammary   Retrievers.
        gland and has become very ill. Bacteria have entered the mammary
        gland and can be fatal if not treated quickly; and 2. Galactostasis:  Meningiomas: Are a kind of brain tumor that affects dogs and
        referred to as caked breasts, galactostasis occurs during the later  arise from the meninges  (the covering  surrounding the brain).
        stages of pregnancy. The milk can start to accumulate and make  Meningiomas are among the most common brain tumors in dogs,
        the  teats  painful  and  distended.  The  mammary  glands  are  not  accounting  for about 40% of all canine  primary  brain tumors.
        infected and therefore the female is not ill. This also happens when  Meningiomas  are  classified  into  three  types:  benign  (Grade
        a female experiences a false pregnancy. Symptoms of mastitis  I), atypical (Grade II), and anaplastic (Grade III or malignant).
        include firm, swollen, warm, and painful mammary gland(s) from  In dogs, the incidence  of Grade I tumors is 50-60%, 40-45%
        which purulent (pus-like) or hemorrhagic fluid can be expressed.  for Grade II tumors, and < 5% for Grade III tumors. Symptoms
        Other symptoms are not wanting to nurse puppies, snapping or  include seizures, confusion or aggression, and loss of equilibrium.
        growling at puppies, discolored or blood in the milk, restlessness,  Boxers, Golden  Retrievers,  Labrador  Retrievers,  and  Miniature
        crying, dehydration, fever, weight loss, and lethargy.     Schnauzers are predisposed to the development of meningiomas.

        Medial  patella  luxation (MPL):  Is a  condition  in  which  the  Meningoencephalomyelitis:  Indicates  inflammation  of  the
        knee-cap no longer glides within its natural groove in the femur,  coverings of the brain and spinal cord, brain tissue itself and spinal
        the upper bone of the knee joint; instead, it becomes displaced  cord tissue. Meningoencephalomyelitis is a compound word that
        to the inside of the joint. MPL is considered congenital and also  indicates inflammation of the meninges (coverings of the brain
        reported to be hereditary. Congenital causes are most common in  and spinal cord), encephalo (brain tissue itself) and myelo (spinal
        small- and toy-breed dogs, including Maltese, Poodles, Yorkshire  cord  tissue).  The  ‘–itis’ part  of the  term  simply  refers  to  the
        Terriers, and others. Larger breed dogs may also be affected by  inflammation. It is uncommon but can be seen in any animals,
        MPL, however, due to trauma or congenital causes. See Luxating  often with devastating results. Symptoms include lethargy, fever,
        patella.                                               disorientation, stupor, seizures, unsteady gait, behavior changes,
                                                               photophobia, stiff neck or back, stumbling, falling, paresis, and
        Megaesophagus: Can be defined as loss of tone and motility of the   paralysis.
        esophagus, often resulting in diffuse dilation and clinical signs of
        regurgitation. It can be either congenital or acquired. Other causes  Metritis: Is the medical term used to describe inflammation of
        of megaesophagus include myasthenia gravis, lead poisoning, and  the endometrium (lining) of the uterus due to a bacterial infection.
        Addison’s disease.  In  addition,  one  study  found  that  peripheral  Unlike  pyometra  (infection  in  the  uterus),  metritis  most  often
        neuropathies, laryngeal paralysis, severe esophagitis (caused by  develops  just  after  giving  birth  and  may  be  associated  with  a
        gastroesophageal reflux, hiatal hernia, Spirocerca lupi infection,  retained fetus or placenta. It can also develop after a natural or


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