Page 8 - Canine-Diseases
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vomiting, depression, lethargy, ataxia, convulsions, reluctance to  lack of appetite, shallow and rapid breathing, faster than normal
        move, intense pruritus, self-mutilation, coma, and sudden death.  pulse, weight loss, black/tarry stools and eating dirt. In addition,
        Mortality in dogs and cats is a hundred per cent. Prevention is  excessive levels of bilirubin (a breakdown product of red blood
        possible by avoiding exposure to pigs or fresh pig products.  cell hemolysis) cause the skin, gums and other mucous membranes
                                                               to  appear  yellow  or  jaundiced. AIHA  can  occur  in  dogs of  all
        Aural haematoma: Bleeding of blood vessels within the pinna   breeds, both sexes, and at any age. But studies suggest it is more
        (or ear flap) resulting in a localised pocket of blood forming in the   prevalent in middle-aged spayed female dogs. This disease is also
        subcutis. The degree of swelling may range from a small area to the   called immune-mediated hemolytic anemia or IMHA.
        entire surface of the pinna. This problem is most often associated
        with underlying ear disease, like excessive head shaking that can
        rupture blood vessels, leading to an ear hematoma. Some of the                  B
        causative factors include grass seed or other foreign body lodged
        within the ear canal, ear infection, allergies resulting in an itchy   Babesiosis:  Refers  to  a  tick-borne  infection  caused  by  various
        ear, scratching and shaking head, fly bites to the tips of the ears,   species of the protozoan genus Babesia (family Ixodidae), or hard
        and immune mediated disease.                           ticks. Some of the species of the genus Babesia that affect dogs

        Autoimmune  disease: Autoimmunity is the system of immune   are B. canis, B. rossi, B. vogeli, B. gibsoni, B. conradae and B.
        responses of an organism against its own healthy cells and   microti-like sp.  The most common mode of transmission is by
        tissues. Any disease that results from such an aberrant immune   tick bite, as the Babesia parasite uses the tick as a reservoir to
        response is termed  an  “autoimmune  disease”.  There  are  many   reach host mammals. Evidence indicates that some direct animal-
        types of autoimmune diseases in dogs including systemic lupus   to-animal transmission may occur, such as when an infected dog
        erythematosus  (SLE),  discoid lupus erythematosus  (DLE),   with oral lesions or abrasions bites another dog. This is particularly
        pemphigus complex (pemphigus vulgaris [PV],  pemphigus   true for Babesia gibsoni, which primarily affects pit bull terriers.
        foliaceus  [PF], pemphigus  erythematosus  [PE],  panepidermal   In addition,  infection  may  occur  by blood  transfusions, or
        pustular pemphigus [PPP], and paraneoplastic pemphigus [PNP]),   transplacental  transmission. Babesiosis can cause hemolytic
        bullous pemphigoid,  Vogt-Koyanagi-Harada-like  syndrome,   anemia in dogs. Dogs that spend a lot of time outdoors, especially
        autoimmune  hemolytic  anemia (AIHA),  Addison’s disease,   in wooded areas, are at an increased risk for tick bites and for
        diabetes, autoimmune  thyroiditis, uveitis, immune-mediated   contracting  this parasite.  This is especially  true in the summer
        thrombocytopenia  (ITP),  inflammatory  bowel  disease,  and   months, from May through September, when tick  populations
        immune-mediated  polyarthritis.  General  symptoms  of canine   are highest. Symptoms include lethargy, anorexia, pale mucous
        autoimmune  disease include muscle weakness, kidney failure,   membranes, weakness, bounding pulse, jaundice, pigmenturia, mild
        abdominal pain, anemia, swollen lymph nodes, dandruff, internal   to severe thrombocytopenia, mild to severe regenerative anaemia
        bleeding, fever, and weight loss. Certain breeds are predisposed to   due to hemolysis, bilirubinemia, bilirubinuria, haemoglobinuria,
        certain types of disease. For example, Chow Chows, Dachshunds,   fever, enlarged abdomen, yellow or orange skin, weight loss, and
        Akitas, and Doberman Pinschers are more likely to develop the   discolored stool. Canine babesiosis was formerly called  canine
        skin disease pemphigus. Whereas, Huskies, Collies, and German   piroplasmosis.  A breed predisposition has been suggested in
        Shepherds are more susceptible to lupus.               Hungary, citing  the  vulnerability  of the  German  Shepherds and
                                                               Komondor breeds to developing babesiosis due to B. canis.
        Autoimmune hemolytic  anemia  (AIHA):  Is an  immune
        system disease in which the body attacks  and destroys its own
        red blood cells. In dogs with  AIHA,  red blood cells are still   Back pain: In dogs, particularly in long-backed breeds, such as
        being manufactured in the bone marrow, but once released into   Basset Hounds and Dachshunds, is usually caused by intervertebral
        the circulation, they have a shorter-than-normal life span. There   disk disease. It is caused by degeneration and protrusion of the disk
        are two forms of AIHA: primary (or idiopathic), and secondary   and compression of the spinal cord. It occurs most commonly in
        AIHA.  With primary  AIHA,  the dog’s dysfunctional immune   the cervical and thoracolumbar regions. Signs include back pain,
        system incorrectly makes antibodies that target its own red blood   hind limb weakness, and paralysis.
        cells. It is estimated that about three-quarters of cases of AIHA
        are primary. With secondary AIHA, the surface of the red blood   Bacterial  folliculitis:  A bacterial  infection  of the hair follicle.
        cells becomes altered by an underlying disease process or a toxin.   The bacteria that infects the hair follicles of pets who suffer this
        The dog’s immune system then recognizes the altered red blood   condition  typically  resides on the  surface  of normal  dog skin.
        cells as ‘foreign’ invaders and are destroyed within the blood   As such, bacterial folliculitis tends to occur when a healthy hair
        vessels by a process called intravascular hemolysis or destroyed   follicle is compromised, either by an underlying systemic disease,
        when they circulate through the liver or spleen by a process called   local trauma, or a specific disorder of the skin. Systemic diseases
        extravascular  hemolysis. Secondary AIHA may be triggered by   that can lead to bacterial folliculitis include endocrine disorders
        cancer, infection, blood parasites such as Babesia, drug reactions,   (such as hypothyroidism and Cushing’s disease in dogs)  and
        snake bites, chemicals, toxins, or bee stings. In dogs, neoplasia or   disorders of the immune system. Skin disorders causing bacterial
        cancer appears to be the most common cause of secondary AIHA.   folliculitis in dogs include: canine acne, acral lick granuloma, skin
        Signs of AIHA include pale gums due to severe anemia, vomiting,   fold pyoderma, interdigital  pododermatitis  (interdigital  cysts),


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